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doi: 10.1038/s41579-018-0141-x 425 Uribe-QuerolE.RosalesC

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Intraperitoneal injection of irisin improves the increase of MDA and the decrease of GSH, SLC7A11 and GPX4 in myocardium, thereby inhibiting ferroptosis, improving cardiac function impairment in diabetic cardiomyopathy mice, and protecting cardiomyocytes from high glucose-induced damage